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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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ISSN Print 0025-5289
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Materiale Plastice (Mater. Plast.), Year 2019, Volume 56, Issue 4, 937-941

https://doi.org/10.37358/MP.19.4.5287

Catalina Radulescu, Daniela Miricescu, Alexandra Totan, Andreea Cristina Didilescu, Iulia-Ioana Stanescu, Radu Radulescu, Ana Maria Alexandra Stanescu, Constantin Stefani, Maria Greabu

Hypercaloric Diet and Vitamin E Intake


Abstract:
PLGA (poly-lactic-co-glycolic acid) nanoparticles represent an important synthetic biocomponent that has the potential to be a promising carrier of drugs, proteins, nucleic acids, due to its biodegradability and minimal side effects. The aim of our study was to observe the antioxidant effect of vitamin E loaded in PLGA nanoparticles administered over a period of 3 weeks in Wistar rats treated with a hypercaloric diet. Glutathione (GSH) and malondiadehyde (MDA) biomarkers determined from liver lysate were analyzed to evaluate the oxidative stress (OS) induced by the hypercaloric diet. The results of our study revealed a statistically significant increase for GSH and vitamin E in group 2 of Wistar rats receiving hypercaloric diet and a daily dose of vitamin E versus group 1 (p<0.005). The antioxidant effect of vitamin E was also observed by the statistically significant decrease of MDA in group 2 of Wistar rats compared with group 1. The daily dose of vitamin E has improved the liver redox status of group 2 Wistar rats.


Keywords:
hypercaloric diet; antioxidant activity; liver

Issue: 2019 Volume 56, Issue 4
Pages: 937-941
Publication date: 2019/12/30
https://doi.org/10.37358/MP.19.4.5287
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
RADULESCU, C., MIRICESCU, D., TOTAN, A., DIDILESCU, A.C., STANESCU, I., RADULESCU, R., STANESCU, A.M.A., STEFANI, C., GREABU, M., Hypercaloric Diet and Vitamin E Intake, Mater. Plast., 56(4), 2019, 937-941.

Vancouver
Radulescu C, Miricescu D, Totan A, Didilescu AC, Stanescu I, Radulescu R, Stanescu AMA, Stefani C, Greabu M. Hypercaloric Diet and Vitamin E Intake. Mater. Plast.[internet]. 2019 Dec;56(4):937-941. Available from: https://doi.org/10.37358/MP.19.4.5287


APA 6th edition
Radulescu, C., Miricescu, D., Totan, A., Didilescu, A.C., Stanescu, I., Radulescu, R.,... Greabu, M. (2019). Hypercaloric Diet and Vitamin E Intake. Materiale Plastice, 56(4), 937-941. https://doi.org/10.37358/MP.19.4.5287


Harvard
Radulescu, C., Miricescu, D., Totan, A., Didilescu, A.C., Stanescu, I., Radulescu, R., Stanescu, A.M.A., Stefani, C., Greabu, M. (2019). 'Hypercaloric Diet and Vitamin E Intake', Materiale Plastice, 56(4), pp. 937-941. https://doi.org/10.37358/MP.19.4.5287


IEEE
C. Radulescu, D. Miricescu, A. Totan, A.C. Didilescu, I. Stanescu, R. Radulescu, A.M.A. Stanescu, C. Stefani, M. Greabu, "Hypercaloric Diet and Vitamin E Intake". Materiale Plastice, vol. 56, no. 4, pp. 937-941, 2019. [online]. https://doi.org/10.37358/MP.19.4.5287


Text
Catalina Radulescu, Daniela Miricescu, Alexandra Totan, Andreea Cristina Didilescu, Iulia-Ioana Stanescu, Radu Radulescu, Ana Maria Alexandra Stanescu, Constantin Stefani, Maria Greabu,
Hypercaloric Diet and Vitamin E Intake,
Materiale Plastice,
Volume 56, Issue 4,
2019,
Pages 937-941,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.4.5287.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5287)
Keywords: hypercaloric diet; antioxidant activity; liver


RIS
TY - JOUR
T1 - Hypercaloric Diet and Vitamin E Intake
A1 - Radulescu, Catalina
A2 - Miricescu, Daniela
A3 - Totan, Alexandra
A4 - Didilescu, Andreea Cristina
A5 - Stanescu, Iulia-Ioana
A6 - Radulescu, Radu
A7 - Stanescu, Ana Maria Alexandra
A8 - Stefani, Constantin
A9 - Greabu, Maria
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 4
SP - 937
EP - 941
UR - https://doi.org/10.37358/MP.19.4.5287
KW - hypercaloric diet
KW - antioxidant activity
KW - liver
ER -


BibTex
@article{MatPlast2019P937,
author = {Radulescu Catalina and Miricescu Daniela and Totan Alexandra and Didilescu Andreea Cristina and Stanescu Iulia-Ioana and Radulescu Radu and Stanescu Ana Maria Alexandra and Stefani Constantin and Greabu Maria},
title = {Hypercaloric Diet and Vitamin E Intake},
journal = {Materiale Plastice},
volume = {56},
number = {4},
pages = {937-941},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.4.5287},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5287}
}
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