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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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ISSN Print 0025-5289
ISSN Online 2668-8220
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Materiale Plastice (Mater. Plast.), Year 2018, Volume 55, Issue 1, 121-123

https://doi.org/10.37358/MP.18.1.4976

Fawzia Sha’at, Ramona Daniela Pavaloiu, Daniela Crina Salceanu, Cristina Hlevca, Gheorghe Nechifor

Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs


Abstract:
The main aim of this study was to prepare and characterize polymeric nanoparticles containing two cardiovascular active pharmaceutical ingredients: valsartan (VAL) and amlodipine besylate (AML). Six formulations were evaluated with different ratios of AML:VAL:PLGA (1:16:17, 1:16:34, and 1:16:51) and different stirring speed (1200 and 2400 rpm). Encapsulation efficiency (EE, %) and particle size analyses were performed to characterize and optimize the formulation. All loaded nanoparticles showed a high EE (%), nano-size, negative x-potential and a high homogeneity.


Keywords:
nanotechnology; cardiovascular drugs; drug delivery systems; medicinal chemistry

Issue: 2018 Volume 55, Issue 1
Pages: 121-123
Publication date: 2018/3/30
https://doi.org/10.37358/MP.18.1.4976
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SHA’AT, F., PAVALOIU, R.D., SALCEANU, D.C., HLEVCA, C., NECHIFOR, G., Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs, Mater. Plast., 55(1), 2018, 121-123.

Vancouver
Sha’at F, Pavaloiu RD, Salceanu DC, Hlevca C, Nechifor G. Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs. Mater. Plast.[internet]. 2018 Jan;55(1):121-123. Available from: https://doi.org/10.37358/MP.18.1.4976


APA 6th edition
Sha’at, F., Pavaloiu, R.D., Salceanu, D.C., Hlevca, C. & Nechifor, G. (2018). Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs. Materiale Plastice, 55(1), 121-123. https://doi.org/10.37358/MP.18.1.4976


Harvard
Sha’at, F., Pavaloiu, R.D., Salceanu, D.C., Hlevca, C., Nechifor, G. (2018). 'Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs', Materiale Plastice, 55(1), pp. 121-123. https://doi.org/10.37358/MP.18.1.4976


IEEE
F. Sha’at, R.D. Pavaloiu, D.C. Salceanu, C. Hlevca, G. Nechifor, "Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs". Materiale Plastice, vol. 55, no. 1, pp. 121-123, 2018. [online]. https://doi.org/10.37358/MP.18.1.4976


Text
Fawzia Sha’at, Ramona Daniela Pavaloiu, Daniela Crina Salceanu, Cristina Hlevca, Gheorghe Nechifor,
Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs,
Materiale Plastice,
Volume 55, Issue 1,
2018,
Pages 121-123,
ISSN 2668-8220,
https://doi.org/10.37358/MP.18.1.4976.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=4976)
Keywords: nanotechnology; cardiovascular drugs; drug delivery systems; medicinal chemistry


RIS
TY - JOUR
T1 - Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs
A1 - Sha’at, Fawzia
A2 - Pavaloiu, Ramona Daniela
A3 - Salceanu, Daniela Crina
A4 - Hlevca, Cristina
A5 - Nechifor, Gheorghe
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2018
VL - 55
IS - 1
SP - 121
EP - 123
UR - https://doi.org/10.37358/MP.18.1.4976
KW - nanotechnology
KW - cardiovascular drugs
KW - drug delivery systems
KW - medicinal chemistry
ER -


BibTex
@article{MatPlast2018P121,
author = {Sha’at Fawzia and Pavaloiu Ramona Daniela and Salceanu Daniela Crina and Hlevca Cristina and Nechifor Gheorghe},
title = {Formulation of Polymeric Multicomponent Systems Containing Cardiovascular APIs},
journal = {Materiale Plastice},
volume = {55},
number = {1},
pages = {121-123},
year = {2018},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.18.1.4976},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=4976}
}
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