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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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Materiale Plastice (Mater. Plast.), Year 2018, Volume 55, Issue 1, 68-74

https://doi.org/10.37358/MP.18.1.4965

Andrada Serafim, Elena Olaret, Sergiu Cecoltan, Livia Maria Butac, Brindusa Balanuca, Eugeniu Vasile, Mihaela Ghica, Izabela Cristina Stancu

Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications


Abstract:
The present paper reports the first attempt to synthesize bicomponent hydrogels based on methacryloyl derivatives of gelatin (GelMA) and mucin (MuMA) with different compositions, with potential as wound dressings. While gelatin is widely investigated and used to fabricate scaffolds and coatings stimulating cell interactions and tissue regeneration, mucin - a macromolecule which covers the wet epithelia - remains yet under exploited as biomaterial. The influence of MuMA content on various parameters such as the affinity for aqueous media, stability in simulated physiologic media and the rheologic behavior was investigated. Also, the preliminary assessment of the drug release potential and biocompatibility were performed. The materials’ water uptake capacity and rheologic behavior depend on the pH value of the incubation media, while their composition influences the drug release capacity and cells-scaffold interactions.


Keywords:
Methacryloyl gelatin; methacryloyl mucin; network-forming polymerization; hydrogels

Issue: 2018 Volume 55, Issue 1
Pages: 68-74
Publication date: 2018/3/30
https://doi.org/10.37358/MP.18.1.4965
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SERAFIM, A., OLARET, E., CECOLTAN, S., BUTAC, L.M., BALANUCA, B., VASILE, E., GHICA, M., STANCU, I.C., Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications, Mater. Plast., 55(1), 2018, 68-74. https://doi.org/10.37358/MP.18.1.4965

Vancouver
Serafim A, Olaret E, Cecoltan S, Butac LM, Balanuca B, Vasile E, Ghica M, Stancu IC. Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications. Mater. Plast.[internet]. 2018 Jan;55(1):68-74. Available from: https://doi.org/10.37358/MP.18.1.4965


APA 6th edition
Serafim, A., Olaret, E., Cecoltan, S., Butac, L.M., Balanuca, B., Vasile, E., Ghica, M. & Stancu, I.C. (2018). Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications. Materiale Plastice, 55(1), 68-74. https://doi.org/10.37358/MP.18.1.4965


Harvard
Serafim, A., Olaret, E., Cecoltan, S., Butac, L.M., Balanuca, B., Vasile, E., Ghica, M., Stancu, I.C. (2018). 'Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications', Materiale Plastice, 55(1), pp. 68-74. https://doi.org/10.37358/MP.18.1.4965


IEEE
A. Serafim, E. Olaret, S. Cecoltan, L.M. Butac, B. Balanuca, E. Vasile, M. Ghica, I.C. Stancu, "Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications". Materiale Plastice, vol. 55, no. 1, pp. 68-74, 2018. [online]. https://doi.org/10.37358/MP.18.1.4965


Text
Andrada Serafim, Elena Olaret, Sergiu Cecoltan, Livia Maria Butac, Brindusa Balanuca, Eugeniu Vasile, Mihaela Ghica, Izabela Cristina Stancu,
Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications,
Materiale Plastice,
Volume 55, Issue 1,
2018,
Pages 68-74,
ISSN 2668-8220,
https://doi.org/10.37358/MP.18.1.4965.
(https://revmaterialeplastice.ro/Articles.asp?ID=4965)
Keywords: Methacryloyl gelatin; methacryloyl mucin; network-forming polymerization; hydrogels


RIS
TY - JOUR
T1 - Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications
A1 - Serafim, Andrada
A2 - Olaret, Elena
A3 - Cecoltan, Sergiu
A4 - Butac, Livia Maria
A5 - Balanuca, Brindusa
A6 - Vasile, Eugeniu
A7 - Ghica, Mihaela
A8 - Stancu, Izabela Cristina
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2018
VL - 55
IS - 1
SP - 68
EP - 74
UR - https://doi.org/10.37358/MP.18.1.4965
KW - Methacryloyl gelatin
KW - methacryloyl mucin
KW - network-forming polymerization
KW - hydrogels
ER -


BibTex
@article{MatPlast2018P68,
author = {Serafim Andrada and Olaret Elena and Cecoltan Sergiu and Butac Livia Maria and Balanuca Brindusa and Vasile Eugeniu and Ghica Mihaela and Stancu Izabela Cristina},
title = {Bicomponent Hydrogels Based on Methacryloyl Derivatives of Gelatin and Mucin with Potential Wound Dressing Applications},
journal = {Materiale Plastice},
volume = {55},
number = {1},
pages = {68-74},
year = {2018},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.18.1.4965},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=4965}
}


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