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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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Materiale Plastice (Mater. Plast.), Year 2017, Volume 54, Issue 1, 190-193

https://doi.org/10.37358/MP.17.1.4814

Maraiana Stuparu Cretu, Ana Camelia Grigore, Adrian Maier, Tudor Ovidiu Popa, Alina Plesea Condratovici, Carmen Dorobat, Liliana Lacramioara Pavel, Ioana Bianca Chesaru

Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience)


Abstract:
Sepsiis syndrome is a common and have devastating implications on health care systems worldwide. Biomarkers may have an important role to highlight the presence, absence or severity of sepsis. Retrospective study was conducted on a group of 81 patients with suspected sepsis, presented in the Emergency Department - Emergency County Hospital St. Spiridon Iasi during 01.09.2014-30.10.2014. The obtained statistical data’s were interpreted using SPSS software and the ROC curve was calculated. The study aims was to establish the following: determining the validity of presepsin as a biological marker in sepsis diagnosis and prognosis; sepsis stratification. The mean age of patients was 64.52 years. Determination of presepsin sensitivity in sepsis early diagnosis was calculated by generating the ROC curve. Following AUC values were found: AUC = 0.709, with a standard error of 0.065 for predicting sepsis; AUC = 0.866, with a standard error of 0.080 for severe sepsis; AUC = 0.864, with a standard error of 0.053 in the presence of septic shock. The average values of presepsin, related with severity of infection, it was found to be 544.39 ± 141.93 pg./mL in case of localized infection; 605.6 ± 59.55 pg./ mL in patients with systemic inflammatory response syndrome; 1283.21 ± 195.74 pg./ mL in patients diagnosed with sepsis; 4787.8 ± 1980.43pg./mL in patients presenting severe sepsis and 3734.88 ± 1732.41pg./mL in patients diagnosed with septic shock. Presepsin level, measured by using quantitative dosage methods, may be helpful in staging patients diagnosed with sepsis and may be used as an indication for initiation of intensive therapy to prevent septic shock. Presepsin level can be used as an early marker of severe prognostic in septic patients.


Keywords:
emergency department; sepsis; biomarker; presepsin

Issue: 2017 Volume 54, Issue 1
Pages: 190-193
Publication date: 2017/3/30
https://doi.org/10.37358/MP.17.1.4814
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
CRETU, M.S., GRIGORE, A.C., MAIER, A., POPA, T.O., CONDRATOVICI, A.P., DOROBAT, C., PAVEL, L.L., CHESARU, I.B., Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience), Mater. Plast., 54(1), 2017, 190-193. https://doi.org/10.37358/MP.17.1.4814

Vancouver
Cretu MS, Grigore AC, Maier A, Popa TO, Condratovici AP, Dorobat C, Pavel LL, Chesaru IB. Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience). Mater. Plast.[internet]. 2017 Jan;54(1):190-193. Available from: https://doi.org/10.37358/MP.17.1.4814


APA 6th edition
Cretu, M.S., Grigore, A.C., Maier, A., Popa, T.O., Condratovici, A.P., Dorobat, C., Pavel, L.L. & Chesaru, I.B. (2017). Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience). Materiale Plastice, 54(1), 190-193. https://doi.org/10.37358/MP.17.1.4814


Harvard
Cretu, M.S., Grigore, A.C., Maier, A., Popa, T.O., Condratovici, A.P., Dorobat, C., Pavel, L.L., Chesaru, I.B. (2017). 'Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience)', Materiale Plastice, 54(1), pp. 190-193. https://doi.org/10.37358/MP.17.1.4814


IEEE
M.S. Cretu, A.C. Grigore, A. Maier, T.O. Popa, A.P. Condratovici, C. Dorobat, L.L. Pavel, I.B. Chesaru, "Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience)". Materiale Plastice, vol. 54, no. 1, pp. 190-193, 2017. [online]. https://doi.org/10.37358/MP.17.1.4814


Text
Maraiana Stuparu Cretu, Ana Camelia Grigore, Adrian Maier, Tudor Ovidiu Popa, Alina Plesea Condratovici, Carmen Dorobat, Liliana Lacramioara Pavel, Ioana Bianca Chesaru,
Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience),
Materiale Plastice,
Volume 54, Issue 1,
2017,
Pages 190-193,
ISSN 2668-8220,
https://doi.org/10.37358/MP.17.1.4814.
(https://revmaterialeplastice.ro/Articles.asp?ID=4814)
Keywords: emergency department; sepsis; biomarker; presepsin


RIS
TY - JOUR
T1 - Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience)
A1 - Cretu, Maraiana Stuparu
A2 - Grigore, Ana Camelia
A3 - Maier, Adrian
A4 - Popa, Tudor Ovidiu
A5 - Condratovici, Alina Plesea
A6 - Dorobat, Carmen
A7 - Pavel, Liliana Lacramioara
A8 - Chesaru, Ioana Bianca
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2017
VL - 54
IS - 1
SP - 190
EP - 193
UR - https://doi.org/10.37358/MP.17.1.4814
KW - emergency department
KW - sepsis
KW - biomarker
KW - presepsin
ER -


BibTex
@article{MatPlast2017P190,
author = {Cretu Maraiana Stuparu and Grigore Ana Camelia and Maier Adrian and Popa Tudor Ovidiu and Condratovici Alina Plesea and Dorobat Carmen and Pavel Liliana Lacramioara and Chesaru Ioana Bianca},
title = {Early Stratification of Sepsis Using Presepsine in Emergency Department (North-East of Romania Experience)},
journal = {Materiale Plastice},
volume = {54},
number = {1},
pages = {190-193},
year = {2017},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.17.1.4814},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=4814}
}


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