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Materiale Plastice
https://doi.org/10.37358/Mat.Plast.1964

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Materiale Plastice, Volume 54, Issue 1, pp. 133-136 (2017)
https://doi.org/10.37358/MP.17.1.4803

Bogdan Andreas Schaas, Sabina Ivan, Monica Titianu, Catalin Plesa Condratovici, Adrian Maier, Carmina Mihaiela Schaas

Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus


Abstract:
Gestational diabetes mellitus (GDM), defined by the occurrence or discovery of glucose intolerance during pregnancy is associated with higher risk of perinatal complications and long-term development of chronic diseases both in the mother and her child. Recent data suggest that women diagnosed earlier in pregnancy, even having more risk factors, develop fewer complications. The aim of the current study is to analyse biochemical markers that play a role in the pathophysiology of GDM and could lead to an early diagnosis. The authors performed a case-control study on 50 pregnant women that finally developed GDM and 50 pregnant women with risk factors for GDM which did non develop the disease. In all cases there were monitored a series of biochemical markers like glycated haemoglobin (HbA1c), sex hormone binding globulin (SHBG), magnesium (Mg), C-reactive protein (CRP), plasma insulin level, and pregnancy-associated plasma protein A (PAPP-A). All these factors were statistically analysed using univariate and multivariate tests in order to evaluate their predicting value. The combination of traditional risk factors with HBA1c, SHBG, PAPP-A and CRP proved significant prognosis value (75% sensitivity rate, 9% false positive rate) for GDM. In conclusion, these four biochemical markers available in early pregnancy have improved the performance of predicting models concerning the development of severe GDM needing insulin treatment and predisposing to maternal and foetal complications.


Keywords:
gestational diabetes mellitus; biochemical markers; glycated haemoglobin; sex hormone binding globhulin

Issue: 2017 Volume 54, Number 1
Pages: 133-136
https://doi.org/10.37358/MP.17.1.4803
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Citation Styles
Cite this article as:
SCHAAS, B.A., IVAN, S., TITIANU, M., CONDRATOVICI, C.P., MAIER, A., SCHAAS, C.M., Mat.Plast., 54, no. 1, 2017, p. 133

Vancouver
Schaas BA, Ivan S, Titianu M, Condratovici CP, Maier A, Schaas CM. Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus. Mat.Plast.[internet]. 2017 Jan;54(1):133-136. Available from: https://revmaterialeplastice.ro/Articles.asp?ID=4803


APA 6th edition
Schaas, B.A., Ivan, S., Titianu, M., Condratovici, C.P., Maier, A. & Schaas, C.M. (2017). Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus. Materiale Plastice, 54(1), 133-136. https://revmaterialeplastice.ro/Articles.asp?ID=4803


Harvard
Schaas, B.A., Ivan, S., Titianu, M., Condratovici, C.P., Maier, A., Schaas, C.M. (2017). 'Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus', Materiale Plastice, 54(1), pp. 133-136. https://revmaterialeplastice.ro/Articles.asp?ID=4803


IEEE
B.A. Schaas, S. Ivan, M. Titianu, C.P. Condratovici, A. Maier, C.M. Schaas, "Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus". Materiale Plastice, vol. 54, no. 1, pp. 133-136, 2017. [online]. https://revmaterialeplastice.ro/Articles.asp?ID=4803


Text
Bogdan Andreas Schaas, Sabina Ivan, Monica Titianu, Catalin Plesa Condratovici, Adrian Maier, Carmina Mihaiela Schaas,
Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus,
Materiale Plastice,
Volume 54, Issue 1,
2017,
Pages 133-136,
ISSN 2668-8220,
https://doi.org/10.37358/MP.17.1.4803.
(https://revmaterialeplastice.ro/Articles.asp?ID=4803)
Keywords: gestational diabetes mellitus; biochemical markers; glycated haemoglobin; sex hormone binding globhulin


RIS
TY - JOUR
T1 - Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus
A1 - Schaas, Bogdan Andreas
A2 - Ivan, Sabina
A3 - Titianu, Monica
A4 - Condratovici, Catalin Plesa
A5 - Maier, Adrian
A6 - Schaas, Carmina Mihaiela
JF - Materiale Plastice
JO - Mat.Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2017
VL - 54
IS - 1
SP - 133
EP - 136
UR - https://revmaterialeplastice.ro/Articles.asp?ID=4803
KW - gestational diabetes mellitus
KW - biochemical markers
KW - glycated haemoglobin
KW - sex hormone binding globhulin
ER -


BibTex
@article{MatPlast2017P133,
author = {Schaas Bogdan Andreas and Ivan Sabina and Titianu Monica and Condratovici Catalin Plesa and Maier Adrian and Schaas Carmina Mihaiela},
title = {Biochemical Markers Predicting the Risk of Gestational Diabetes Mellitus},
journal = {Materiale Plastice},
volume = {54},
number = {1},
pages = {133-136},
year = {2017},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.17.1.4803},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=4803}
}

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